Chemistry and Biochemistry

Physical Sciences Building
Room 339 (lab) / 354 (office)
1156 High Street
Santa Cruz, CA 95064





© 2008 The Regents of the University of California

Maintained by ngassner@ucsc.edu


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The optical density of zones of death from 384 compounds pinned into soft agar yeast plates are used to predict compound potency.

Our Capabilities

The UCSC Chemical Screening Center offers access to:

  • Equipment:  a suite of modern robotic instrumentation that permits high-throughput biochemical and cell-based screening of up to 30,000 compounds a day.
  • Libraries:  diversity, targeted and known drug libraries and a growing collection of natural products.
  • Technical Assistance:  assay development, screening, data processing and cherry picking. 
  • Screens:  in diverse organisms that pair compounds with a broad bioactivity profile based on potency and phenotype. 
  • Data Analysis: compound and assay data archiving and mining. 


Apply now


The optical density of zones of death from 384 compounds pinned into soft agar yeast plates are used to predict compound potency.


Center Highlights

CNBC Tech Effect segment highlights UCSC Chemical Screening Center
CNBC Tech Effect segment gives an overview of how UCSC Chemical Screening Center robotics assist with discovery of new drugs from the sea.
 [more]
UCSC Chemical Screening Center marine natural product research featured on National Public Radio
Listen to audio from Quest science program to hear about the search for drugs from the ocean floor.
 [more]
UCSC Chemical Screening Center robotics featured on KQED Quest Science show
View video of UCSC Chemistry Screening Center robots featured on KQED's Quest Science program.
 [more]
KQED's Quest science program slideshow surveys UCSC Chemical Screening Center marine natural product research
View a slideshow that gives an overview of how the UCSC Chemical Screening Center helps identify new marine natural products.
 [more]
UCSC Chemical Screening Center featured in Silicon Valley/San Jose Business Journal
Link
Finding Chemo: Scanning the Sea Floor for New Drugs
The UCSC Chemical Screening Center's robotics and unique natural product libraries were featured on Wired.com Link
UCSC's Chemical Screening Center celebrates a year on 'the cutting edge"
The Chemical Screening Center's First Annual Symposium was highlighted in the Santa Cruz Sentinel.Link
November 14 symposium marks a productive first year for UCSC's Chemical Screening Center
In its first year of operation, the UCSC Chemical Screening Center has enabled researchers to identify a variety of potentially useful compounds, including promising leads for the development of new drugs to treat infections, cancer, and neglected diseases such as malaria and African sleeping sickness.Link
Chemical Screening Center at UCSC will search for new drugs
Researchers at the University of California, Santa Cruz, will shift their search for potential drugs into high gear on September 21, when a new Chemical Screening Center opens for business. The center will allow researchers to perform up to 30,000 experiments per day as they test chemical compounds for usefulness in fighting disease or understanding fundamental aspects of a cell's life. A half-day symposium will mark the opening day. [more]